Microsoft 365 is a productivity cloud that delivers intelligent experiences, enterprise-grade management, and advanced security to take your business further. Office 365 is a suite of productivity apps and services including Outlook, Word, Excel, and more. FEATURE Office 365 E3 Microsoft 365 E3 Office 365 E3 The M365 vs O365 Comparison Chart below shows all the details. Compare Microsoft 365 E3 vs Office 365 E3Ĭompare Office 365 to Microsoft 365 and discover features available to both M365 as well as O365 and other features only available with m365.